| 产品名称 | A-196 |
| 产品货号 | Axon 2705 CAS [1982372-88-2] MF C18H16Cl2N4MW 359.25 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description A-196 is a potent and selective inhibitor of SUV420H1 and SUV420H2 ((IC50 values of 25 and 144 nM, respectively). In cells, A-196 induced a global decrease in H4K20me2 and H4K20me3 and a concomitant increase in H4K20me1. A-196 inhibited 53BP1 foci formation upon ionizing radiation and reduced NHEJ-mediated DNA-break repair but did not affect homology-directed repair. KEYWORDS: A-196 | supplier | SUV4-20 inhibitor | A196 | A 196 | CAS [1982372-88-2] | Non Selective (Lysine Sites Proteins) | PKMT | Inhibitor | Enzymes | Protein Lysine Methyltransferase | Histone Methyltransferase | SUV420H1 | SUV420H2 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
A-196Axon 2705 CAS [1982372-88-2] MF C18H16Cl2N4
DescriptionA-196 is a potent and selective inhibitor of SUV420H1 and SUV420H2 ((IC50 values of 25 and 144 nM, respectively). In cells, A-196 induced a global decrease in H4K20me2 and H4K20me3 and a concomitant increase in H4K20me1. A-196 inhibited 53BP1 foci formation upon ionizing radiation and reduced NHEJ-mediated DNA-break repair but did not affect homology-directed repair. KEYWORDS: A-196 | supplier | SUV4-20 inhibitor | A196 | A 196 | CAS [1982372-88-2] | Non Selective (Lysine Sites Proteins) | PKMT | Inhibitor | Enzymes | Protein Lysine Methyltransferase | Histone Methyltransferase | SUV420H1 | SUV420H2
Potent and selective inhibitor of SUV4-20
Chemical name6,7-Dichloro-N-cyclopentyl-4-(pyridin-4-yl)phthalazin-1-amine Parent CAS No.[1982372-88-2] |
| 产品资料 |
