产品名称 | AMI-1 - AMI-1 sodium salt |
产品货号 | Axon 2863 CAS [20324-87-2] MF C21H14N2Na2O9S2MW 548.45 Purity: 99% Soluble in water and DMSO Description AMI-1 specifically inhibits protein arginine N-methyltransferase (PRMT) activity in vitro (IC50 values of 8.81 and 3.04 µM for PRMT1 and Hmt1p, respectively). Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. HIV-1 integrase inhibitor (IC50 value of 4 µM). KEYWORDS: AMI-1 | supplier | PRMT inhibitor | AMI-1 sodium salt | AMI 1 | AMI1 | CAS [20324-87-2] | [134-47-4] | Non Selective (Arginine Sites Proteins) | PRMT | Inhibitor | Enzymes | HIV-1 | Integrase | Protein Arginine N-Methyltransferase |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | |
产品品牌 | axonmedchem |
产品概述 | |
产品详情 |
AMI-1 - AMI-1 sodium saltAxon 2863 CAS [20324-87-2] MF C21H14N2Na2O9S2
DescriptionAMI-1 specifically inhibits protein arginine N-methyltransferase (PRMT) activity in vitro (IC50 values of 8.81 and 3.04 µM for PRMT1 and Hmt1p, respectively). Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. HIV-1 integrase inhibitor (IC50 value of 4 µM). KEYWORDS: AMI-1 | supplier | PRMT inhibitor | AMI-1 sodium salt | AMI 1 | AMI1 | CAS [20324-87-2] | [134-47-4] | Non Selective (Arginine Sites Proteins) | PRMT | Inhibitor | Enzymes | HIV-1 | Integrase | Protein Arginine N-Methyltransferase
Inhibitor of PRMT
Chemical nameSodium 7,7'-carbonylbis(azanediyl)bis(4-hydroxynaphthalene-2-sulfonate) Parent CAS No.[134-47-4] |
产品资料 |