产品名称

BI-D1870

产品货号

Axon 1528 CAS [501437-28-1] MF C19H23F2N5O2MW 391.42 Purity: 99% Soluble in DMSO and Ethanol Description Potent and specific inhibitor of the p90 ribosomal S6 kinase (RSK) isoforms in vitro and in vivo, which inhibits RSK1, RSK2, RSK3 and RSK4 in vitro (IC50 values 31 nM, 24 nM, 18 nM, and 15 nM, respectively).* BI-D1870 binds at NTKD binding site as a reversible RSK inhibitor, while FMK (Axon 1848) binds at CTKD site as an irreversible RSK inhibitor. KEYWORDS: BI-D1870 | supplier | RSK inhibitor | BID1870 | BID-1870 | CAS [501437-28-1] | p90-RSK | p90 ribosomal S6 kinase | RSK1 | RSK2 | RSK3 | RSK4 | NTKD binding site | reversible

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

BI-D1870

Based on 177 publications in PubMed 9 10 177

Axon 1528

CAS [501437-28-1]

MF C19H23F2N5O2
MW 391.42

Purity: 99%
Soluble in DMSO and Ethanol

BI-D1870

Description

Potent and specific inhibitor of the p90 ribosomal S6 kinase (RSK) isoforms in vitro and in vivo, which inhibits RSK1, RSK2, RSK3 and RSK4 in vitro (IC50 values 31 nM, 24 nM, 18 nM, and 15 nM, respectively).
* BI-D1870 binds at NTKD binding site as a reversible RSK inhibitor, while FMK (Axon 1848) binds at CTKD site as an irreversible RSK inhibitor.

KEYWORDS: BI-D1870 | supplier | RSK inhibitor | BID1870 | BID-1870 | CAS [501437-28-1] | p90-RSK | p90 ribosomal S6 kinase | RSK1 | RSK2 | RSK3 | RSK4 | NTKD binding site | reversible