产品名称

A 943931

产品货号

Axon 1990 CAS [1027330-97-7] MF C17H21N5MW 295.38 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Potent and selective histamine H4 receptor antagonist References Certificates Categories Extra info MD Cowart et al. Rotationally constrained 2,4-diamino-5,6-disubstituted pyrimidines: a new class of histamine H4 receptor antagonists with improved druglikeness and in vivo efficacy in pain and inflammation models. J. Med. Chem. 2008, 51, 6547. R Leurs et al. Molecular and biochemical pharmacology of the histamine H4 receptor. Br. J. Pharmacol. 2009, 157, 14. RA Smits et al. Major advances in the development of histamine H4 receptor ligands. Drug Disc. Today. 2009, 14(15-16), 745. Certificate of Analysis Material Safety Data Sheet CNS Immunology H4 A18 H4 antagonist Chemical name 4-[(3R)-3-aminopyrrolidin-1-yl]-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-amine Parent CAS No. [1027330-97-7] Order Size Unit Price Stock 2 mg €75.00 In Stock

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现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

A 943931

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1990

CAS [1027330-97-7]

MF C17H21N5
MW 295.38

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

A 943931

Description

Potent and selective histamine H4 receptor antagonist

MD Cowart et al. Rotationally constrained 2,4-diamino-5,6-disubstituted pyrimidines: a new class of histamine H4 receptor antagonists with improved druglikeness and in vivo efficacy in pain and inflammation models. J. Med. Chem. 2008, 51, 6547.

R Leurs et al. Molecular and biochemical pharmacology of the histamine H4 receptor. Br. J. Pharmacol. 2009, 157, 14.

RA Smits et al. Major advances in the development of histamine H4 receptor ligands. Drug Disc. Today. 2009, 14(15-16), 745.

CNS Immunology H4 A18

H4 antagonist

Chemical name

4-[(3R)-3-aminopyrrolidin-1-yl]-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-amine

Parent CAS No.

[1027330-97-7]

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