产品名称 MK 5108 - VX 689
产品货号 Axon 1961 CAS [1010085-13-8] MF C22H21ClFN3O3SMW 461.94 Purity: 98% Optical purity: Optically pure Soluble in DMSO Description Highly potent and selective inhibitor of Aurora A kinase (AurA); MK5108 exhibits marked effects on the growth of tumor cells in vitro and in vivo; also enhances the antitumoractivity of Docetaxel without exacerbrating the toxicity in vivo References Certificates Categories Extra info T Shimomura et al. MK-5108, a highly selective Aurora-A kinase inhibitor, shows antitumor activity alone and in combination with docetaxel. Mol. Cancer Ther. 2010, 9(1), 157-166.  Certificate of Analysis Material Safety Data Sheet Cell Cycle Regulation Cell Signaling & Oncology Epigenetics EC 2.7.11.1 Aurora Inhibitor of Aurora A kinase Chemical name (1r,4r)-4-(3-chloro-2-fluorophenoxy)-1-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)cyclohexanecarboxylic acid Parent CAS No. [1010085-13-8] Order Size Unit Price Stock 5 mg €110.00 In Stock
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MK 5108 - VX 689

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1961

CAS [1010085-13-8]

MF C22H21ClFN3O3S
MW 461.94

  • Purity: 98%
  • Optical purity: Optically pure
  • Soluble in DMSO

MK 5108

Description

Highly potent and selective inhibitor of Aurora A kinase (AurA); MK5108 exhibits marked effects on the growth of tumor cells in vitro and in vivo; also enhances the antitumoractivity of Docetaxel without exacerbrating the toxicity in vivo
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