产品名称

Blebbistatin, (±)-

产品货号

Axon 2718 CAS [674289-55-5] MF C18H16N2O2MW 292.33 Purity: 99% Soluble in DMSO Description Blebbistatin is a potent and specific inhibitor of the motor functions of class II myosins (IC50 values of 6.47, 3.58, 2.30 and 1.57 μM for inhibiting actin-activated ATPase activities of SmM, NM2a, NM2b and NM2c, respectively). Blebbistatin inhibited contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Moreover, Blebbistatin inhibited both the ATPase and gliding motility activities of human platelet nonmuscle myosin II without inhibiting myosin light chain kinase. KEYWORDS: (±)-Blebbistatin | Myosin II inhibitor | Blebbistatin | CAS [674289-55-5] | ATP | ATPase (myosin) | Inhibitor | Enzymes

产品价格

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产品规格

产品品牌

axonmedchem

产品概述

产品详情

Blebbistatin, (±)-

Based on 626 reference(s) in Google Scholar 8 10 626

Axon 2718

CAS [674289-55-5]

MF C18H16N2O2
MW 292.33

Purity: 99%
Soluble in DMSO

Blebbistatin, (±)-

Description

Blebbistatin is a potent and specific inhibitor of the motor functions of class II myosins (IC50 values of 6.47, 3.58, 2.30 and 1.57 μM for inhibiting actin-activated ATPase activities of SmM, NM2a, NM2b and NM2c, respectively). Blebbistatin inhibited contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Moreover, Blebbistatin inhibited both the ATPase and gliding motility activities of human platelet nonmuscle myosin II without inhibiting myosin light chain kinase.