产品名称

Hydroxy-DPAT hydrobromide, (R)-5- - DPAT, (R)-5-OH-

产品货号

Axon 1007 CAS [182210-73-7] MF C16H25NO.HBrMW 328.29 Purity: 98% Optical purity: >98% ee Soluble in DMSO Description While racemic 5-OH-DPAT (Axon 1006) is a potent and selective dopamine (DA) D2-receptor agonist, its R-enantiomer, (R)-5-OH DPAT is a weakly potent DA D2-receptor antagonist References Certificates Categories Extra info A Karlsson et al. (R)- and (S)-5-hydroxy-2-(dipropylamino)tetralin (5-OH DPAT): Assessment of optical purities and dopaminergic activities. Chirality. 1989-1995, 2(2), 90-95. S.L. Payne et al. Mechanisms of ligand binding and efficacy at the human D2(short) dopamine receptor. J. Neurochem. 2002, 82, 1106–1117. Certificate of Analysis Material Safety Data Sheet CNS D2 A17 D2 antagonist Chemical name (R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol hydrobromide Parent CAS No. [69367-51-7] Order Size Unit Price Stock 5 mg €145.00 In Stock

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axonmedchem

产品概述

产品详情

Hydroxy-DPAT hydrobromide, (R)-5- - DPAT, (R)-5-OH-

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1007

CAS [182210-73-7]

MF C16H25NO.HBr
MW 328.29

Purity: 98%
Optical purity: >98% ee
Soluble in DMSO

Hydroxy-DPAT hydrobromide, (R)-5-

Description

While racemic 5-OH-DPAT (Axon 1006) is a potent and selective dopamine (DA) D2-receptor agonist, its R-enantiomer, (R)-5-OH DPAT is a weakly potent DA D2-receptor antagonist

A Karlsson et al. (R)- and (S)-5-hydroxy-2-(dipropylamino)tetralin (5-OH DPAT): Assessment of optical purities and dopaminergic activities. Chirality. 1989-1995, 2(2), 90-95.

S.L. Payne et al. Mechanisms of ligand binding and efficacy at the human D2(short) dopamine receptor. J. Neurochem. 2002, 82, 1106–1117.

CNS D2 A17

D2 antagonist

Chemical name

(R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol hydrobromide

Parent CAS No.

[69367-51-7]

产品资料