产品名称 SB 431542
产品货号 Axon 1661 CAS [301836-41-9] MF C22H16N4O3MW 384.39 Purity: 99% Soluble in DMSO Description Potent and selective inhibitor of TGF-β1 superfamily activin receptor-like kinase (ALK), specifically at ALK5 (IC50: 94 nM) and its relatives ALK4 (IC50: 140 nM) and ALK7; SB431542 inhibits endogenous activin and TGF-β signaling, but has no effect on BMP signaling; a useful tool for studing the role of TGF-β, activin and many cellular processes. *Promotion
产品价格 现货询价,电话:010-67529703
产品规格
产品品牌 axonmedchem
产品概述
产品详情

SB 431542

Based on 413 publications in PubMed 10 10 413

Axon 1661

CAS [301836-41-9]

MF C22H16N4O3
MW 384.39

  • Purity: 99%
  • Soluble in DMSO

SB 431542

Description

Potent and selective inhibitor of TGF-β1 superfamily activin receptor-like kinase (ALK), specifically at ALK5 (IC50: 94 nM) and its relatives ALK4 (IC50: 140 nM) and ALK7; SB431542 inhibits endogenous activin and TGF-β signaling, but has no effect on BMP signaling; a useful tool for studing the role of TGF-β, activin and many cellular processes.

*Promotion: SB 431542 is also part of Inhibitor Set(s):

Axon 5004 Axon 5005 Axon 5007
Axon 5009


KEYWORDS: SB 431542 | supplier | ALK5 inhibitor | SB431542 | CAS [301836-41-9] | TGF-β1 | TGF-beta | RSTK | activin receptor-like kinase | BMP signaling | Transforming Growth Factor | osteosarcoma

产品资料