产品名称 | SB 431542 | ||||
产品货号 | Axon 1661 CAS [301836-41-9] MF C22H16N4O3MW 384.39 Purity: 99% Soluble in DMSO Description Potent and selective inhibitor of TGF-β1 superfamily activin receptor-like kinase (ALK), specifically at ALK5 (IC50: 94 nM) and its relatives ALK4 (IC50: 140 nM) and ALK7; SB431542 inhibits endogenous activin and TGF-β signaling, but has no effect on BMP signaling; a useful tool for studing the role of TGF-β, activin and many cellular processes. *Promotion | ||||
产品价格 | 现货询价,电话:010-67529703 | ||||
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产品品牌 | axonmedchem | ||||
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产品详情 |
SB 431542Axon 1661 CAS [301836-41-9] MF C22H16N4O3
DescriptionPotent and selective inhibitor of TGF-β1 superfamily activin receptor-like kinase (ALK), specifically at ALK5 (IC50: 94 nM) and its relatives ALK4 (IC50: 140 nM) and ALK7; SB431542 inhibits endogenous activin and TGF-β signaling, but has no effect on BMP signaling; a useful tool for studing the role of TGF-β, activin and many cellular processes. *Promotion: SB 431542 is also part of Inhibitor Set(s):
List of publications using SB 431542 (Axon 1661) purchased from Axon Medchem
TGF-βR1 inhibitor; ALK inhibitor
Chemical name4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide Parent CAS No.[301836-41-9] |
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