产品名称

Cabozantinib S-malate - XL 184

产品货号

Axon 1819 CAS [1140909-48-3] MF C28H24FN3O5.C4H6O5MW 635.59 Purity: 99% Soluble in DMSO Description A orally available and potent inhibitor of multiple receptor tyrosine kinases (RTK), specifically MET and VEGFR2. It also inhibits KIT, FLT3, Tie-2, RET and AXL References Certificates Categories Extra info M Yakes et al. Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Mol. Cancer Ther. 2011, 10(12), 2298-2308. Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology Axl c-MET FLT3 VEGFR c-KIT RTK class IV and X; EC 2.7.10.1 Inhibitor of multiple receptor tyrosine kinases, specifically MET and VEGFR2 Chemical name N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-2-hydroxysuccinate Parent CAS No. [849217-68-1] Order Size Unit Price Stock 10 mg €85.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

Cabozantinib S-malate - XL 184

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1819

CAS [1140909-48-3]

MF C28H24FN3O5.C4H6O5
MW 635.59

Purity: 99%
Soluble in DMSO

Cabozantinib S-malate

Description

A orally available and potent inhibitor of multiple receptor tyrosine kinases (RTK), specifically MET and VEGFR2. It also inhibits KIT, FLT3, Tie-2, RET and AXL

M Yakes et al. Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Mol. Cancer Ther. 2011, 10(12), 2298-2308.

Angiogenesis Cell Signaling & Oncology Axl c-MET FLT3 VEGFR c-KIT RTK class IV and X; EC 2.7.10.1

Inhibitor of multiple receptor tyrosine kinases, specifically MET and VEGFR2

Chemical name

N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-2-hydroxysuccinate

Parent CAS No.

[849217-68-1]

产品资料