产品名称

RET Inhibitor 2667

产品货号

Axon 2667 CAS [1980023-80-0] MF C26H25FN10OMW 512.54 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Potent RET inhibitor (IC50 value <10 nM) with activity against wild-type RET and its mutants. KEYWORDS: RET inhibitor 2667 | supplier | RET inhibitor | CAS [1980023-80-0] | RTK | GDNF | RET | Receptor tyrosine kinase | oncology | breast cancer | proliferation

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

RET Inhibitor 2667

Based on 1 reference(s) in Google Scholar 9 10 1

Axon 2667

CAS [1980023-80-0]

MF C26H25FN10O
MW 512.54

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

RET Inhibitor 2667

Description

Potent RET inhibitor (IC50 value <10 nM) with activity against wild-type RET and its mutants.

KEYWORDS: RET inhibitor 2667 | supplier | RET inhibitor | CAS [1980023-80-0] | RTK | GDNF | RET | Receptor tyrosine kinase | oncology | breast cancer | proliferation

PE Fleming et al. Preparation of 2-(pyridin-3-yl)-pyrimidine derivatives as RET inhibitors. PCT Int. Appl. (2016), WO 2016127074 A1 20160811

Apoptosis Cell Signaling & Oncology Pain & Inflammation RET RTK class XIV; EC 2.7.10.1

Potent RTK inhibitor with activity against wild-type RET and its mutants

Chemical name

(S)-N-(1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethyl)-3-methyl-5-(4-methyl-6-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2-yl)picolinamide

Parent CAS No.

[1980023-80-0]

产品资料