| 产品名称 | CP 547632 |
| 产品货号 | Axon 1662 CAS [252003-65-9] MF C20H24BrF2N5O3SMW 532.40 Purity: 98% Soluble in DMSO Description A potent and oral tyrosine kinase inhibitor (TKI), targeting VEGFR2 and basic FGF kinases (IC50 to be 11 and 9 nM respectively); selective relative to EGFR, PDGF-ß, and other related TKs; inhibits VEGF-stimulated autophosphorylation of VEGFR2 in a whole cell assay with an IC50 value of 6 nM References Certificates Categories Extra info JS Beebe et al. Pharmacological Characterization of CP-547,632, a Novel Vascular Endothelial Growth Factor Receptor-2 Tyrosine Kinase Inhibitor for Cancer Therapy. Cancer Res. 2003, 63, 7301-7309. Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology VEGFR RTK class IV; EC 2.7.10.1 VEGFR2 tyrosine kinase inhibitor Chemical name 3-(4-bromo-2,6-difluorobenzyloxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carboxamide Parent CAS No. [252003-65-9] Order Size Unit Price Stock 2 mg €105.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
CP 547632Axon 1662 CAS [252003-65-9] MF C20H24BrF2N5O3S
Description
A potent and oral tyrosine kinase inhibitor (TKI), targeting VEGFR2 and basic FGF kinases (IC50 to be 11 and 9 nM respectively); selective relative to EGFR, PDGF-ß, and other related TKs; inhibits VEGF-stimulated autophosphorylation of VEGFR2 in a whole cell assay with an IC50 value of 6 nM
VEGFR2 tyrosine kinase inhibitor
Chemical name3-(4-bromo-2,6-difluorobenzyloxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carboxamide Parent CAS No.[252003-65-9] |
| 产品资料 |
