产品名称

AEE 788 - NVP-AEE 788

产品货号

Axon 1653 CAS [497839-62-0] MF C27H32N6MW 440.58 Purity: 98% Optical purity: >98% ee Soluble in 0.1N HCl(aq) and DMSO Description A dual family EGFR/ErbB2 and VEGFR kinase inhibitor with antitumor and antiangiogenic activity References Certificates Categories Extra info P Traxier, PR Allegrini, R Brandt et al. AEE788: A dual family EGFR/ErbB2 and VEGFR kinase inhibitor with antitumor and antiangiogenic activity. Cancer Res. 2004, 64, 4931-4941. D Meco et al. Dual Inhibitor AEE788 Reduces Tumor Growth in Preclinical Models of Medulloblastoma. Transl. Oncol. 2010, 3(5), 326-335. Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology EGFR VEGFR ErbB2-HER2 JAK-STAT RTK class I and IV; EC 2.7.10.1 EGFR, ErbB2 and VEGFR tyrosine kinase inhibitor Chemical name (R)-6-(4-((4-ethylpiperazin-1-yl)methyl)phenyl)-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Parent CAS No. [497839-62-0] Order Size Unit Price Stock 5 mg €95.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

AEE 788 - NVP-AEE 788

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1653

CAS [497839-62-0]

MF C27H32N6
MW 440.58

Purity: 98%
Optical purity: >98% ee
Soluble in 0.1N HCl(aq) and DMSO

AEE 788

Description

A dual family EGFR/ErbB2 and VEGFR kinase inhibitor with antitumor and antiangiogenic activity

P Traxier, PR Allegrini, R Brandt et al. AEE788: A dual family EGFR/ErbB2 and VEGFR kinase inhibitor with antitumor and antiangiogenic activity. Cancer Res. 2004, 64, 4931-4941.

D Meco et al. Dual Inhibitor AEE788 Reduces Tumor Growth in Preclinical Models of Medulloblastoma. Transl. Oncol. 2010, 3(5), 326-335.

Angiogenesis Cell Signaling & Oncology EGFR VEGFR ErbB2-HER2 JAK-STAT RTK class I and IV; EC 2.7.10.1

EGFR, ErbB2 and VEGFR tyrosine kinase inhibitor

Chemical name

(R)-6-(4-((4-ethylpiperazin-1-yl)methyl)phenyl)-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Parent CAS No.

[497839-62-0]

产品资料