| 产品名称 | Vatalanib - PTK 787 |
| 产品货号 | Axon 1637 CAS [212141-54-3] MF C20H15ClN4MW 346.81 Purity: 98% Soluble in DMSO Description A potent and selective inhibitor of tyrosine kinases, targeting VEGFR, with IC50 to be 77 nM (VEGFR1), 37 nM (VEGFR2), 580 nM (PDGFR-β), 730 nM (c-KIT), 660 nM (FLT-4) and 1.4 µM (c-FMS) respectively; not active against EGFR, SRC-ABL and PKC etc References Certificates Categories Extra info JM Wood et al. PTK787/ZK 222584, a Novel and Potent Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases (...). Cancer Res. 2000, 60, 2178-2189. EN Scott et al. Vatalanib: the clinical development of a tyrosine kinase inhibitor of angiogenesis in solid tumours. Expert Opin Investig Drugs 2007, 16(3), 367–379. Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology VEGFR RTK class IV; EC 2.7.10.1 VEGFR tyrosine kinase inhibitor Chemical name N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine Parent CAS No. [212141-54-3] Order Size Unit Price Stock 10 mg €75.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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Vatalanib - PTK 787Axon 1637 CAS [212141-54-3] MF C20H15ClN4
Description
A potent and selective inhibitor of tyrosine kinases, targeting VEGFR, with IC50 to be 77 nM (VEGFR1), 37 nM (VEGFR2), 580 nM (PDGFR-β), 730 nM (c-KIT), 660 nM (FLT-4) and 1.4 µM (c-FMS) respectively; not active against EGFR, SRC-ABL and PKC etc
VEGFR tyrosine kinase inhibitor
Chemical nameN-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine Parent CAS No.[212141-54-3] |
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