| 产品名称 | CI 1033 - Canertinib dihydrochloride |
| 产品货号 | Axon 1433 CAS [289499-45-2] MF C24H25ClFN5O3.2HClMW 558.86 Purity: 99% Soluble in water and DMSO Description An orally bioavailable tyrosine kinase inhibitor, targeting EGFR, irreversibly inhibiting their signal transduction functions and resulting in tumor cell apoptosis and suppression of tumor cell proliferation; water-soluble form References Certificates Categories Extra info PA. Jänne et al. Multicenter, Randomized, Phase II Trial of CI-1033, an Irreversible Pan-ERBB Inhibitor, for Previously Treated Advanced Non–Small-Cell Lung Cancer. J. Clinic. Oncology, 2007, 25(25), 3936-3944. E Calvo et al. Administration of CI-1033, an Irreversible Pan-erbB Tyrosine Kinase Inhibitor, Is Feasible on a 7-Day On, 7-Day Off Schedule. A Phase I Pharmacokinetic and Food Effect Study. Clinical Cancer Research 2004, 10, 7112-7120. LV Sequist. Second-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer. The Oncologist, 2007, 12(3), 325-330. Certificate of Analysis Material Safety Data Sheet Angiogenesis Apoptosis Cell Signaling & Oncology EGFR JAK-STAT RTK class I; EC 2.7.10.1 EGFR tyrosine kinase inhibitor Chemical name N-[4-(3-Chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide dihydrochloride Parent CAS No. [267243-28-7] Order Size Unit Price Stock 5 mg €60.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
CI 1033 - Canertinib dihydrochlorideAxon 1433 CAS [289499-45-2] MF C24H25ClFN5O3.2HCl
Description
An orally bioavailable tyrosine kinase inhibitor, targeting EGFR, irreversibly inhibiting their signal transduction functions and resulting in tumor cell apoptosis and suppression of tumor cell proliferation; water-soluble form
EGFR tyrosine kinase inhibitor
Chemical nameN-[4-(3-Chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide dihydrochloride Parent CAS No.[267243-28-7] |
| 产品资料 |
