| 产品名称 | GW 786034 - Pazopanib hydrochloride |
| 产品货号 | Axon 1420 CAS [635702-64-6] MF C21H23N7O2S.HClMW 473.98 Purity: 98% Soluble in DMSO Description A potent and selective inhibitor of tyrosine kinases, targeting VEGFR/c-KIT/PDGFR, blocking angiogenesis; as an oral antineoplastic agent References Certificates Categories Extra info G Sonpavde et al. Pazopanib, a potent orally administered small-molecule multitargeted tyrosine kinase inhibitor for renal cell carcinoma. Exp. Opin. Invest. Drugs. 2008, 17(2), 253-261. G Sonpavde and TE Hutson. Pazopanib: a novel multitargeted tyrosine kinase inhibitor. Curr. Oncol. Rep. 2007, 9(2), 115-9. K Podar et al. The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma. Proc. Natl. Acad. Sci. USA. 2006, 103(51), 19478-19483. Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology VEGFR PDGFR c-KIT RTK class III and IV; EC 2.7.10.1 PDGFR, c-KIT and VEGFR tyrosine kinase inhibitor Chemical name 5-{4-[(2,3-Dimethyl-2H-indazol-6-yl)-methyl-amino]-pyrimidin-2-ylamino}-2-methyl-benzenesulfonamide hydrochloride Parent CAS No. [444731-52-6] Order Size Unit Price Stock 5 mg €70.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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GW 786034 - Pazopanib hydrochlorideAxon 1420 CAS [635702-64-6] MF C21H23N7O2S.HCl
Description
A potent and selective inhibitor of tyrosine kinases, targeting VEGFR/c-KIT/PDGFR, blocking angiogenesis; as an oral antineoplastic agent
PDGFR, c-KIT and VEGFR tyrosine kinase inhibitor
Chemical name5-{4-[(2,3-Dimethyl-2H-indazol-6-yl)-methyl-amino]-pyrimidin-2-ylamino}-2-methyl-benzenesulfonamide hydrochloride Parent CAS No.[444731-52-6] |
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