产品名称

Sunitinib malate - SU 11248 | Sutent

产品货号

Axon 1398 CAS [341031-54-7] MF C22H27FN4O2.C5H8O4MW 530.59 Purity: 99% Soluble in DMSO Description Small molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. Sunitinib inhibits cellular signaling by targeting multiple RTKs, including PDGF-R/VEGF-R. KEYWORDS: Sunitinib malate | supplier | PDGFR inhibitor | SU 11248 | Sutent | SU11248 | SU-11248 | CAS [341031-54-7] | [557795-19-4] | SCF | PDGF | VEGF | c-KIT | PDGFR | VEGFR | RTK | receptor tyrosine kinase

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

Sunitinib malate - SU 11248 | Sutent

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1398

CAS [341031-54-7]

MF C22H27FN4O2.C5H8O4
MW 530.59

Purity: 99%
Soluble in DMSO

Sunitinib malate

Description

Small molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. Sunitinib inhibits cellular signaling by targeting multiple RTKs, including PDGF-R/VEGF-R.

KEYWORDS: Sunitinib malate | supplier | PDGFR inhibitor | SU 11248 | Sutent | SU11248 | SU-11248 | CAS [341031-54-7] | [557795-19-4] | SCF | PDGF | VEGF | c-KIT | PDGFR | VEGFR | RTK | receptor tyrosine kinase

J Motzer et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007, 356(2), 115–124.

ED Deeks and GM Keating. Sunitinib. Drugs 2006, 66, 2255-2266.

TJ Abrams et al. SU11248 Inhibits KIT and Platelet-derived Growth Factor Receptor β in Preclinical Models of Human Small Cell Lung Cancer. Mol. Cancer Ther. 2003, 2, 471-478.

Angiogenesis Cell Signaling & Oncology VEGFR PDGFR c-KIT RTK class III and IV; EC 2.7.10.1 Pfizer Licensed Products

Multi-targeted receptor tyrosine kinase inhibitor

Chemical name

N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide malate

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[557795-19-4]

产品资料