产品名称 | Haptoglobin, Human Plasma, Mixed Type | Athens Research & Technology |
产品货号 | 16-16-080116 |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | size |
产品品牌 | Athens Research |
产品概述 | |
产品详情 |
PRODUCT NUMBER:16-16-080116Buy Purified Native Human Haptoglobin direct from manufacturer.
Salt-free lyophilized solid. Storage: -20°C An acute-phase plasma protein found in human plasma at 100-300 mg per 100 ml. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes: Hp 1-1, Hp 2-1, and Hp 2-2. While the phenotypic distribution can vary greatly between ethnicities and geographic location, the Hp 2-1 phenotype is the most prevalent phenotype in humans. Plasma concentrations of haptoglobin are highest in individuals with Hp 1-1, intermediate in Hp 2-1 individuals, and lowest in Hp 2-2 individuals. Hp 1-1 is the most effective at binding hemoglobin, and Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype.
Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. Athens Research & Technology products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research use only.
Gunasena, Dilani N., and Ziad El Rassi. "Hydrophilic diol monolith for the preparation of immuno‐sorbents at reduced nonspecific interactions."Journal of separation science 34.16‐17 (2011): 2097-2105.
Sakamoto K, et al.
Kozlik P, Goldman R, Sanda M.
Eshbach ML, et al. Hemoglobin inhibits albumin uptake by proximal tubule cells: implications for sickle cell disease.
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