产品名称Flurbiprofen
产品货号F8514
产品价格现货询价,电话:010-67529703
产品规格F8514
产品品牌sigmaaldrich
产品详情

Description

Packaging

1, 5, 25 g in poly bottle

Application

Flurbiprofen is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic, analgesic, and antifungal activity. Oral formulations of flurbiprofen may be used to treat rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen is also used topically during ocular surgery to prevent or reduce intraoperative miosis. Flurbiprofen is structurally and pharmacologically related to ibuprofen. It is used to study the pathophysiological steps of NSAID enteropathy in the rat and the biotransformation of flurbiprofen by Cunninghamella species.

Biochem/physiol Actions

Fluibiprofen is a cyclooxygenase (COX) inhibitor, which is an enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This decreases the prostaglandins which cause inflammation, pain, swelling and fever. Flurbiprofen inhibits the activity of both COX-1 and -2. The S enantiomer inhibits prostaglandin synthesis and has both anti-inflammatory and analgesic activity, while the R enantiomer does not inhibit prostaglandin synthesis and displays only analgesic activity.

产品资料下载链接
51.La 网站流量统计系统    京ICP备11041154号                       来宝网
全国客服热线:400-650-8506,(86)-010-57218832,(86)-010-57129146,(86)-010-82986680 传真:(86)-010-67529703

市场部信箱:sales@bio-goods.com,技术部信箱:tech@bio-goods.com,人事部信箱:jobs@bio-goods.com
世联博研(北京)科技有限公司,单位地址:北京市海淀区西三旗上奥世纪中心A座9层906,邮编:100096