The 1800 series is the reinforced plunger version of the 1700 series syringe. Attached to the flange of the syringe is a removable blue syringe holder that prevents heat transfer, dispense inaccuracies and plunger blow outs. It also provides support to small volume plungers that are prone to bending during injection.

They have a precision machined PTFE plunger tip which creates a leak-free seal

Cemented needles for low volume syringes are cemented into the glass syringe barrel at a point corresponding to the zero graduation mark. With this termination, dead volume is limited to the internal volume of the needle. Not autoclavable. Needle gauge is determined by the syringe volume and are not user-selectable.

Removable needles are a Hamilton-specific design. The design allows the needles to seat precisely at the zero graduation mark of the syringe. Users can select the needle gauge, length, and point style to optimize the syringe for custom applications. This termination also allows for a removable needle without increasing the dead volume of the syringe and is ideal when there is a risk of the needle clogging. Autoclavable when disassembled. Repeated autoclaving will shorten syringe life.

Needle point style 2 is a sharp, beveled, curved, non-coring needle point recommended for septum penetration.