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Product Name | GTP 14564 |
Description | Potent, selective inhibitor of class III receptor tyrosine kinases (IC50 values are 0.3 μM for c-Fms, c-Kit, FLT3 and ITD-FLT3 and 1 μM for PDGFRβ). Displays no activity against ERK1, ERK2, EGFR, MEK1, HER2, Src, Abl, PKC, PKA and Akt (IC50 > 10 μM). Inhibits FL-dependent proliferation in BaF/ITD-FLT3 cells more potently than BaF/wt-FLT3 cells; anti-leukemic. Purity 99%. MW (observed): 234.26 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3-Phenyl-1H-benzofuro[3,2-c]pyrazole |
Gene, Accession, CAS # | CAS: 34823-86-4 |
Catalog # | 2086/10 |
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Order / More Info | GTP 14564 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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