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Product Name | B7-2/CD86, 31-247aa, Human, His-Tag, Baculovirus |
Description | Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. B7-2/CD86, also known as T-lymphocyte activation antigen CD86 isoform 1, is a variably glycosylated protein in the B7 family. These family members play important roles in immune activation and the maintenance of immune tolerance. It is expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival and exists predominantly as a monomer on cell surfaces. Also, it interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells that it induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. Recombinant Human B7-2/CD86, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Size | 100ug, 20ug, 10ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | B7-2/CD86, CD86, B7-2, B7.2, B70, CD28LG2, LAB72, T-lymphocyte activation antigen CD86, Activation B7-2 antigen, B70, BU63, CTLA-4 counter-receptor B7.2, FUN-1 |
Gene, Accession, CAS # | NP_787058 |
Catalog # | ATGP3895 |
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Order / More Info | B7-2/CD86, 31-247aa, Human, His-Tag, Baculovirus from ATGen |
Product Specific References | n/a |
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