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Product Name | Pyr3 |
Description | Selective antagonist of the canonical transient receptor potential channel 3 (TRPC3). Inhibits TRPC3-mediated Ca2+ influx (IC50 = 0.7 μM) and suppresses activation of nuclear factor of activated T cells (NFAT). Inhibits hypertrophic responses in cardiomyocytes. Purity 98%. MW (observed): 456.63 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid |
Gene, Accession, CAS # | CAS: 1160514-60-2 |
Catalog # | 3751/10 |
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Order / More Info | Pyr3 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 23325252, 23948776, 24843004, 25873305 |
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