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Product Name | SuGT1, 115-365aa, Human, His tag, E.coli |
Description | Purity: > 90% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 1mM DTT, 0.1M NaCl . SuGT1, also known as suppressor of G2 allele of SKP1, is a homolog of the yeast protein SGT1, a regulator of the cell cycle that is essential for G1/S and G2/M transitions. It contains a CS domain, a SGS domain, a p23 domain and three tetratricopeptide repeats (TPR). This protein associates with Skp1 p19 and CuL-1, subunits of the SCF ubiquitin ligase complex, and is thought to play a role in protein degradation. In addition, it is required for the kinetochores assembly, and has function as a co-chaperone for HSP90. Recombinant human SuGT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Suppressor of G2 allele of SKP1 homolog isoform SGT1B, SGT1 |
Gene, Accession, CAS # | NP 001124384 |
Catalog # | ATGP0899 |
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Order / More Info | SuGT1, 115-365aa, Human, His tag, E.coli from ATGen |
Product Specific References | n/a |
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