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| Product Name | CDK2, 1-298aa, Human, His tag, Baculovirus |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate buffered saline (pH7.4), 30% glycerol, 2mM DTT, 0.1mM PMSF . Cyclin-dependent kinase 2, also known as CDK2, phosphorylates CTNNB1, uSP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. This protein acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. This protein is crucial role in orchestrating a fine balance between cellular proliferation, cell death, and DNA repair in human embryonic stem cells (hESCs). Recombinant human CDK2 protein, fused to His-tag at C-terminus, was expressed in insect cells using baculovirus expression system and purified by using conventional chromatography techniques. |
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| Size | 250ug, 50ug, 10ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Cyclin-dependent kinase 2, p33 (CDK2) |
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| Gene, Accession, CAS # | NP 001789 |
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| Catalog # | ATGP2878 |
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| Order / More Info | CDK2, 1-298aa, Human, His tag, Baculovirus from ATGen |
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| Product Specific References | n/a |
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