| 产品详情 |
| Edit |   |
|---|
| Product Name | SCO2, 42-266aa, Human, His tag, E.coli |
|---|
| Description | Purity: > 90% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 2mM DTT, 200mM NaCl . SCO2 protein belongs to the SCO1/2 family of proteins. Both SCO1 and SCO2 proteins are located on the inner membrane of the mitochondria and plays a crucial role in copper insertion or transport to the active site of cytochrome c oxidase (COX). Defects in SCO2 are the cause of fatal infantile cardioencephalomyopathy with cytochrome c oxidase deficiency (FIC). This disease is characterized by hypertrophic cardiomyopathy, lactic acidosis, and gliosis. Heart and skeletal muscle show reductions in cytochrome c oxidase (COX) activity, whereas liver and fibroblasts show mild COX deficiencies. Recombinant human SCO2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
|---|
| Size | 250ug, 50ug, 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | SDS-PAGE |
|---|
| Other Names | Protein SCO2 homolog mitochondrial, Protein SCO2 homolog mitochondrial, SCO1L |
|---|
| Gene, Accession, CAS # | NP 005129 |
|---|
| Catalog # | ATGP0867 |
|---|
| Price | |
|---|
| Order / More Info | SCO2, 42-266aa, Human, His tag, E.coli from ATGen |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|