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Product Name | CSTB, 1-98aa, Human, His tag, E.coli (Bioactivity Validated) |
Description | Purity: > 95% by SDS - PAGE Format: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 50mM NaCl. CSTB, also known as Cystatin B is an anti-protease implicated in myoclonus epilepsy, a degenerative disease of the central nervous system. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. This protein is able to form a dimer stabilized by noncovalent forces and is thought to play a role in protecting against the proteases leaking from lysosomes. In cells, CSTB is located in the lysosomes and the cytoplasm, but also in the nucleus. Recombinant CSTB, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques. |
Size | 50ug, 10ug, |
Concentration | n/a |
Applications | Enzyme activity |
Other Names | Cystatin-B, Stefin B, PME, CST6 |
Gene, Accession, CAS # | NP 000091 |
Catalog # | ATGP3262 |
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Order / More Info | CSTB, 1-98aa, Human, His tag, E.coli (Bioactivity Validated) from ATGen |
Product Specific References | n/a |
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