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Product Name | PRKAB1, 1-270aa, Human, His tag, E.coli |
Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT . 5'-AMP-activated protein kinase subunit beta-1, also known as PRKAB1, inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). Recombinant human PRKAB1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Size | 50ug, 10ug, |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | 5'-AMP-activated protein kinase subunit beta-1, AMPK, HAMPKb |
Gene, Accession, CAS # | NP 006244 |
Catalog # | ATGP1786 |
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Order / More Info | PRKAB1, 1-270aa, Human, His tag, E.coli from ATGen |
Product Specific References | n/a |
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