| 产品详情 |
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| Product Name | NAV 2729 |
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| Description | Selective ARF6 inhibitor (IC50 = 1.0 μM). Selective for ARF6 over other ARF family members and small GTPases. Inhibits ARF6 activation in uveal melanoma cells in vitro and blocks downstream signaling pathways of oncogenic GNAQ. Reduces tumorigenesis in mouse model of uveal melanoma. Purity 98%. MW (observed): 456.88 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-(4-Chlorophenyl)-5-(4-nitrophenyl)-2-(phenylmethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one |
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| Gene, Accession, CAS # | CAS: 419547-11-8 |
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| Catalog # | 5986/50 |
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| Price | |
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| Order / More Info | NAV 2729 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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