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| Product Name | Interleukin-3, 20-152aa, Human, His tag, E.coli (Bioactivity Validated) |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid in 20mM Tris pH 8.0, 0.2mM PMSF, 10% glycerol. Interleukin-3(IL-3) stimulates the proliferation of hematopoietic pluripotent progenitor cells. It is secreted by activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response. IL-3 exerts its biological activities through binding to specific cell surface receptors. IL-3 receptor is a complex consisting of alpha and beta subunits, which in turn induces activation of JAK2/ STAT5, induction of c-myc, and activation of the Ras pathway. Human IL3 is a protein of 15-17 kDa (133 amino acids). It is synthesized as a precursor containing a hydrophobic secretory signal sequence of 19 amino acids. IL3 contains two putative glycosylation sites at positions 15 and 70 and contains a single disulfide bond (Cys16/84). Recombinant human IL-3 was expressed in E.coli and purified by using conventional chromatography after refolding of the isolated inclusion bodies in a redox buffer. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | Bioactivity |
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| Other Names | IL-3, Multipotential colony-stimulating factor(multi-CSF), Mast cell growth factor(MCGF), interleukin 3 (colony-stimulating factor, multiple), MuLTI-CSF, MCGF, multilineage-colony-stimulating factor, hematopoietic growth factor, P-cell stimulating factor, mast-cell growth factor |
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| Gene, Accession, CAS # | AAC08706 |
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| Catalog # | ILC0702 |
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| Order / More Info | Interleukin-3, 20-152aa, Human, His tag, E.coli (Bioactivity Validated) from ATGen |
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| Product Specific References | n/a |
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