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Product Name | DKK3, 22-350aa, Human, His tag, E.coli (Denatured) |
Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1M urea,10% glycerol, 1mM DTT. Dickkopf-related protein 3, also known as DKK3, is a member of the DKK protein family including Dkk-1, 2, 3 and -4. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. DKK3 is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Recombinant human DKK3 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Dickkopf-related protein 3 precursor, REIC, RIG |
Gene, Accession, CAS # | NP 001018067 |
Catalog # | ATGP1666 |
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Order / More Info | DKK3, 22-350aa, Human, His tag, E.coli (Denatured) from ATGen |
Product Specific References | n/a |
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