产品详情 |
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Antigenic Specificity | B7-RP1 (CD275, ICOSL, B7H2) |
Clone | HK5.3 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | phycoerythrin (PE) conjugate |
Size | 50 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-mouse CD275 (B7-RP1, ICOSL, B7H2). CD275 is a 40 kD protein, also known as ICOS ligand, B7-RP1, B7-H2, and B7h. It is a member of the immunoglobulin receptor superfamily expressed on splenic B cells, dendritic cells, and macrophages. The expression of this antigen is increased by TNF-α stimulation and is highly upregulated by local inflammation. B7RP1 binds to ICOS and co-stimulates T cell and B cell responses. Two isoforms of this protein have been reported to occur as a result of alternative splicing. These isoforms show differential tissue distribution. |
Immunogen | Mouse B7-RP1 transfected cell line |
Other Names | ICOSL, B7RP1, B7-H2, B7h |
Gene, Accession # | Gene ID: 50723 |
Catalog # | 107405 |
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Order / More Info | B7-RP1 (CD275, ICOSL, B7H2) Antibody from BIOLEGEND |
Product Specific References | PubMed: 17182586,21276089 |
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