产品详情 |
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Antigenic Specificity | CD117 |
Clone | 104D2 |
Host Species | Mouse |
Reactive Species | human, cross-reactivity: cynomolgus, cow |
Isotype | IgG1, κ |
Format | Brilliant Violet 785™ conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Brilliant Violet 785™ anti-human CD117 (c-kit). CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells. |
Immunogen | MOLM-1 megakaryocytic cell line |
Other Names | c-KIT, Stem Cell Factor Receptor (SCFR) |
Gene, Accession # | Gene ID: 3815 |
Catalog # | 313238 |
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Order / More Info | CD117 Antibody from BIOLEGEND |
Product Specific References | PubMed: 17379743 |
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