产品详情 |
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Antigenic Specificity | CD127 |
Clone | A7R34 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | Alexa Fluor® 647 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 647 anti-mouse CD127 (IL-7Rα). CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development. |
Immunogen | IL-7Ra-IgG1 fusion protein |
Other Names | IL-7 receptor α chain, IL-7Rα |
Gene, Accession # | Gene ID: 16197 |
Catalog # | 135020 |
Price | |
Order / More Info | CD127 Antibody from BIOLEGEND |
Product Specific References | PubMed: 21209281,21653324 |
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