产品详情 |
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Antigenic Specificity | CD119 (IFN-g R a chain) |
Clone | 2E2 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | purified |
Size | 500 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IP, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse CD119 (IFN-γ R α chain). CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses. |
Immunogen | Soluble recombinant mouse IFN-γR α chain protein |
Other Names | IFN-γRα , IFN-γ Receptor α chain, CDw119 |
Gene, Accession # | Gene ID: 15979 |
Catalog # | 112802 |
Price | |
Order / More Info | CD119 (IFN-g R a chain) Antibody from BIOLEGEND |
Product Specific References | n/a |
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