| 产品详情 |
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| Antigenic Specificity | CD221 (IGF-1R) |
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| Clone | 1H7/CD221 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, baboon, cynomolgus, rhesus |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IHC, IP, Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human CD221 (IGF-1R). CD221, also known as insulin-like growth factor 1 receptor (IGF1R), is a 135 kD transmembrane receptor. It is widely expressed on lymphoid and myeloid cells as well as non-haematopoietic cells. CD221 is a tyrosine kinase receptor and the ligands for CD221 are insulin-like growth factor 1 and 2 (IGF-1 and IGF-2), the polypeptide hormones similar in molecular structure to insulin. IGF-1/2 binding activates downstream PI3K and MAPK pathways and plays an important role in cell growth. Recent studies reveal its function of recruiting immune cells during tissue repair. |
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| Immunogen | IGF-1 receptor purified from human placentas |
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| Other Names | Insulin-like growth factor 1 receptor |
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| Gene, Accession # | Gene ID: 3480 |
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| Catalog # | 351802 |
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| Price | |
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| Order / More Info | CD221 (IGF-1R) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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