产品详情 |
Edit |   |
Antigenic Specificity | CD4 |
Clone | H129.19 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | fluorescein (FITC) conjugate |
Size | 500 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FITC anti-mouse CD4. CD4 is a 55 kD protein, also known as L3T4 or T4. It is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin kinase, lck. The H129.19 antibody is able to block CD4 mediated cell adhesion and T cell activation. It is also useful for in vivo and in vitro depletion of CD4+ T cells. H129.19 antibody blocks binding of the anti-mouse CD4 mAbs GK1.5 and RM4-5, but not RM4-4 antibody. H129.19 antibody inhibits various responses of T helper cells to antigenic or mitogenic stimuli. |
Immunogen | Mouse lymphocytes |
Other Names | L3T4, T4 |
Gene, Accession # | Gene ID: 12504 |
Catalog # | 130308 |
Price | |
Order / More Info | CD4 Antibody from BIOLEGEND |
Product Specific References | n/a |
产品资料 |
|
|