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| Antigenic Specificity | Human CD278 (ICOS) |
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| Clone | C398.4A |
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| Host Species | Armenian Hamster |
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| Reactive Species | human, African green, baboon, cynomolgus, mouse, rat, rhesus, porcine |
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| Isotype | IgG |
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| Format | TotalSeq™-C oligomer conjugate |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | Proteogenomics. TotalSeq™ reagents are designed to profile protein expression at a single cell level following an optimized protocol similar to the CITE-seq workflow. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TotalSeq™-C0171 anti-human/mouse/rat CD278 (ICOS). ICOS, also known as inducible costimulatory molecule and H4, is a 47-57 kD protein. This protein is homologous to the CD28/CTLA-4 proteins. ICOS is expressed on activated T cells and a subset of thymocytes. It is able to costimulate T cells proliferation. In addition, ICOS is involved in humoral immune responses (B cell germinal center formation). The ICOS ligand is B7h/B7RP-1 or B7-H2. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to play a role in Th2 cell development. |
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| Immunogen | Mouse T cell clone D10.G4.1 |
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| Other Names | Inducible COStimulatory molecule, H4 |
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| Gene, Accession # | Gene ID: 100048841, 29851, 64545 |
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| Catalog # | 313553 |
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| Price | |
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| Order / More Info | Human CD278 (ICOS) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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