| 产品详情 |
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| Antigenic Specificity | CD317 (BST2, umanPDCA-1) |
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| Clone | 927 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2b, κ |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC anti-mouse CD317 (BST2, PDCA-1). CD317, known as BST2, tetherin, HM1.2 antigen, bone marrow stromal antigen 2, or PDCA-1, is type II transmembrane glycoprotein with a molecular mass of 29-33 kD. It is predominantly expressed on Type I IFN-producing cells (IPCs) in naïve mice, but is up-regulated on most cell types following stimulation with type I IFNs and IFN-gamma. It is highly expressed on terminally differentiated normal plasmacytoid dendritic cells and some tumor cells, such as multiple myeloma, renal cell carcinoma, and melanoma cells. BST2 is a recently identified, IFN-induced cellular response factor that blocks release of HIV-1 and other retroviruses from infected cells. BST2 has been found to be the natural ligand of ILT7 in human model. |
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| Immunogen | Mouse plasmacytoid dendritic cells (DCs) |
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| Other Names | BST2, PDCA-1, plasmacytoid DC (pDC) Ag-1, plasmacytoid DC |
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| Gene, Accession # | Gene ID: 69550 |
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| Catalog # | 127016 |
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| Price | |
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| Order / More Info | CD317 (BST2, umanPDCA-1) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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