产品详情 |
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Antigenic Specificity | Mac-3 |
Clone | M3/84 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | purified |
Size | 50 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse CD107b (Mac-3). Mac-3 is a 110 kD type I membrane glycoprotein, also known as CD107b and LAMP-2. It is expressed on lysosomal membranes and the plasma membrane of macrophages and some myeloid cell lines. In the bone marrow, few cells display Mac-3 antigen on the surface, but a large proportion express Mac-3 in the cytoplasm. CD107b has been identified as a ligand for galaptin, an S-type lectin present in the extracellular matrix. Mac-3/CD107b is upregulated in some tumors and increased expression has been correlated with enhanced metastatic potential. |
Immunogen | Membrane glycoproteins from C57BL/6 mouse peritoneal exudate cells |
Other Names | CD107b, LAMP-2, Mac3 |
Gene, Accession # | Gene ID: 16784 |
Catalog # | 108501 |
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Order / More Info | Mac-3 Antibody from BIOLEGEND |
Product Specific References | PubMed: 16126211,21127056 |
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