产品详情 |
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Antigenic Specificity | CD49d |
Clone | K49 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 50 tests, 100 tests |
Concentration | n/a |
Applications | FACS, ICC, IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal to CD49d.K49 reacts with a-4 integrin chain, which is expressed as a heterodimer with either of b1 (CD29) or b7. The a4b1 integrin (VLA-4) is present on lymphocytes, monocytes, thymocytes, NK cells, dendritic cells, erythroblastic precursor but absent on normal red blood cells, platelets and neutrophils. The a4b1 integrin mediated binding to VCAM-1 (CD106) and the CS-1 region of fibronectin. CD49d is involved in multiple inflammatory responses through the regulation of lymphocyte migration and T cell activation; CD49d also is essential for the differentiation and traffic of hematopoietic stem cells. |
Immunogen | n/a |
Other Names | CD49d (FITC) |
Gene, Accession # | n/a |
Catalog # | orb12083 |
Price | |
Order / More Info | CD49d Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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