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| Product Name | Recombinant Saccharomyces cerevisiae Nicotinamidase (PNC1) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 29kDa. Full Length: 1-216aa. N-terminal 6xHis-tagged. Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). Catalyzes the deamidation of nicotinamide, an early step in the NAD+ salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress. Acts also on nicotinyl hydroxamate. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Nicotine deamidase; NAMase |
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| Gene, Accession, CAS # | PNC1, UniProt: P53184 |
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| Catalog # | RPC20366 |
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| Order / More Info | Recombinant Saccharomyces cerevisiae Nicotinamidase (PNC1) from BIOMATIK |
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| Product Specific References | n/a |
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