产品详情 |
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Antigenic Specificity | HtrA2/Omi |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, k |
Format | purified |
Size | 100ul, 50ul |
Concentration | n/a |
Applications | ELISA, WB, IF/ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HtrA2/Omi is a mammalian serine protease at high temperatures and a chaperone at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain; an inhibitor of apoptosis protein (IAP)-binding motif; a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death. |
Immunogen | Recombinant human HtrA2 (134-458aa) purified from E.coli. |
Other Names | High temperature requirement protein A2, HTRA2, OMI, PRSS25, HtrA2/Omi, EC 3.4.21.108, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine proteinase OMI, Serine protease 25, Serine protease HTRA2, mitochondrial, High temperature requirement protein A2 |
Gene, Accession # | NP 037379 |
Catalog # | ATGA0342 |
Price | |
Order / More Info | HtrA2/Omi Antibody from ATGen |
Product Specific References | n/a |
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