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| Product Name | uBE2D1, 1-147aa, Human, His tag, E.coli |
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| Description | Purity: > 95% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.1M NaCl. uBE2D1 belongs to the ubiquitin-conjugating enzyme family. ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. uBE2D1 is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Recombinant human uBE2D1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | ubiquitin-conjugating enzyme E2D 1, SFT, uBC5A, uBCH5, uBCH5A |
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| Gene, Accession, CAS # | NP 003329 |
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| Catalog # | ATGP1074 |
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| Order / More Info | uBE2D1, 1-147aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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