产品详情 |
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Antigenic Specificity | RLIM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, hamster, human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB, IF, IHC, ChIP, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-Mouse RLIM polyclonal antibody for WB, IF, IHC, ChIP, ICC. E3 ubiquitin-protein ligase RLIM (UniProt Q9WTV7; also known as Hoxa1 regulated, LIM domain-interacting RING finger protein, R-LIM, RING finger LIM domain-binding protein, Ring finger protein 12) is encoded by the Rlim (also known as AL022832, AW743871, Ha1r, Rlim1, Rnf12) gene (Gene ID 19820) in murine species. The CLIM/LDB/NLI and RLIM/RNF12 cofactors are transcriptional coregulatory proteins characterized by their ability to bind the LIM domains of nuclear LIM proteins, including LIM homeodomain (LIM-HD) transcription factors. The association of CLIM with LIM-HDs positively regulate their biological and transcriptional activity. On the other hand, the RING finger ubiquitin ligase RLIM acts as a negative regulator of LIM-HD activity by interacting with and targeting CLIM for degradation via the ubiquitin-proteasome pathway. |
Immunogen | Recombinant Protein |
Other Names | n/a |
Gene, Accession # | UniProt: Q9WTV7 |
Catalog # | CABT-B1930 |
Price | |
Order / More Info | RLIM Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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