产品详情 |
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Antigenic Specificity | RNASEH2A (internal region) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB, ELISA, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-Human RNASEH2A polyclonal antibody for WB, ELISA, ICC. The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009] |
Immunogen | Synthetic peptide |
Other Names | n/a |
Gene, Accession # | Gene ID: 10535, UniProt: O75792 |
Catalog # | CABT-BL3160 |
Price | |
Order / More Info | RNASEH2A (internal region) Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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