| 产品详情 |
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| Antigenic Specificity | Axin1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor® 488 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Axin1 Polyclonal Antibody, Alexa Fluor® 488 Conjugated. • Target Background: Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. In Wnt signaling, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B. Likely to function as a tu |
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| Immunogen | KLH conjugated synthetic peptide derived from human Axin1 . Immunogen Range: 830-862/862 |
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| Other Names | AXIN; PPP1R49; Axin-1; Axis inhibition protein 1; hAxin; AXIN1 |
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| Gene, Accession # | Gene ID: 8312, SwissProt: O15169 |
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| Catalog # | bs-2439R-A488 |
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| Price | |
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| Order / More Info | Axin1 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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