产品详情 |
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Antigenic Specificity | Axin1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 100ul |
Concentration | 1ug/ul |
Applications | WB, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Axin1 Polyclonal Antibody, HRP Conjugated. • Target Background: Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. In Wnt signaling, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B. Likely to function as a tu |
Immunogen | KLH conjugated synthetic peptide derived from human Axin1 . Immunogen Range: 830-862/862 |
Other Names | AXIN; PPP1R49; Axin-1; Axis inhibition protein 1; hAxin; AXIN1 |
Gene, Accession # | Gene ID: 8312, SwissProt: O15169 |
Catalog # | bs-2439R-HRP |
Price | |
Order / More Info | Axin1 Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |
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