| 产品详情 |
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| Antigenic Specificity | DHX36 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | Protein G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA, IF |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DHX36 Antibody LS-C501706. Specificity: Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component (TERC) 5'-end (nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5'-end to promote P1 helix formation; the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification. |
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| Immunogen | Recombinant Human ATP-dependent RNA helicase DHX36 protein (68-181AA) |
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| Other Names | DHX36, DEAH box protein 36, DDX36, G4R1, MLE-like protein 1, G4 resolvase-1, KIAA1488, MLEL1, RHAU |
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| Gene, Accession # | DHX36, Gene ID: 170506 |
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| Catalog # | LS-C501706 |
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| Price | |
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| Order / More Info | DHX36 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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