| 产品详情 |
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| Product Name | PD-150606 |
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| Description | Purity >98% by NMR, TLC. PD-150606 is a selective, cell-permeable non-peptide calpain inhibitor (Ki for u- and m-calpains = 0.21 and 0.37 uM respectively). Acts at the calcium binding site of calpain rather than the substrate-binding site. Inhibits calpain activity in two intact cell systems. Attenuates hypoxic/hypoglycemic injury to cerebrocortical neurons in culture and excitotoxic injury to Purkinje cells in cerebellar slices. PD-150606 displays cytoprotective effects in oxidant- and calcium ionophore-induced cell death. Some protective effects may be due to inhibition of MMP activity. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic acid |
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| Gene, Accession, CAS # | CAS: 179528-45-1 |
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| Catalog # | LS-H14802 |
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| Order / More Info | PD-150606 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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