| 产品详情 |
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| Product Name | 1-Stearoyl-2-Arachidonoyl-sn-Glycerol |
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| Description | Purity >95%. Many protein kinase C (PKC) isoforms require activation via second messengers including Ca2+, diacylglycerol (DAG), and/or a phospholipid to phosphorylate target proteins and they initiate a variety of important signalling cascades. 1-Stearoyl-2-arachidonoyl-sn -glycerol (SAG) is a DAG that contains the Omega-6 polyunsaturated fatty acid arachidonic acid in the sn -2 position and stearic acid in the sn -1 position of the glycerol backbone. It can potently activate PKCAlpha, PKCe, and PKCDelta at nM concentrations. Independent of PKC signalling, SAG competitively binds to the Ras activator RasGRP with a Ki value of 4.49 µM in Jurkat T-cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn -glycerol, SAG |
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| Gene, Accession, CAS # | CAS: 65914-84-3 |
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| Catalog # | LS-H5921 |
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| Price | |
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| Order / More Info | 1-Stearoyl-2-Arachidonoyl-sn-Glycerol from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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